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. 2001 Feb 28;6(3):142–193. doi: 10.3390/60300142

Figure 1.

Figure 1

Muscarinic receptors at different locations along the autonomic parasympathetic efferent pathway. Acetylcholine (Ach) released from the preganglionic varicosity can interact with nicotinic NN, muscarinic M1 and muscarinic M2 receptors to produce a fast depolarisation (fast EPSP), a slow depolarization (slow EPSP) and hyperpolarization (IPSP), respectively. Nicotinic receptor stimulation sets up the action potential in the postganglionic neurone to release Ach from parasympathetic nerve terminal varicosities. This can interact with M2 or M3 receptors in smooth muscle.