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. 2001 Apr 30;6(5):448–467. doi: 10.3390/60500448
Peptide IC50
hY1
[nM]
IC50 (Pep)
IC50 (NPY)
hY2
[nM]
IC50 (Pep)
IC50 (NPY)
hY4
[nM]
IC50 (Pep) IC50 (NPY) hY5
[nM]
IC50 (Pep)
IC50 (NPY)
pNPY 0.23 (1) 0.04 (1) 5.5 (1) 0.8 (1)
[A1]-pNPY 21 (91) 0.2 (5) 5.8 (1.1) 2.2 (2.8)
[A2]-pNPY 114 (496) 0.3 (8) 7.8 (1.4) 5.5 (7)
[A5]-pNPY 228 (991) 24 (600) 25 (4.5) 32 (40)
[A8]-pNPY 32 (139) 0.7 (18) 60 (11) 55 (69)
[A11]-pNPY 8.0 (35) 0.2 (5) 3.1 (0.6) 0.5 (0.6)
[A13]-pNPY 7.5 (33) 0.1 (3) 37 (6.7) 17 (21)
[A19]-pNPY 282 (1226) 1.6 (40) 4.1 (0.7) 1.4 (1.8)
[A20]-pNPY 71 (309) 1.2 (30) 161 (29) 19 (24)
[A21]-pNPY 5.5 (24) 0.2 (5) 66 (12) 32 (40)
[A25]-pNPY 11 (48) 0.7 (18) 201 (37) 80 (100)
[A27]-pNPY 250 (1087) 1.4 (35) 340 (62) 370 (463)
[A32]-pNPY 723 (3143) 45 (1125) 380 (69) 7.7 (9.5)
[A33]-pNPY >1000 (>4348) 54 (1350) >1000 (>182) 94 (118)
[A34]-pNPY 94 (409) 6.0 (150) 7.4 (1.3) 1.3 (1.6)
[A35]-pNPY >1000 (>4348) >1000 (>25000) >1000 (>182) >1000 (>1250)
[A36]-pNPY 970 (4217) 48 (1200) 141 (26) 68 (85)
[L34]-pNPY 0.3 (0.05) 1.8 (2.3)
[D-P34]-pNPY 266 (1157) 271 (49) 156 (195)
[Ahx5-24]-NPY >1000 (>4348) 1.4 (35) 600 (109) 795 (994)
[Ahx5-24, P34]-NPY >1000 (>4348) 514 (93) >10000 (>12500)
[Ahx8-20]-NPY 28 (122) 67 (12) 31 (39)
[Ahx8-19]-NPY 46 (200) 95 (17) 19 (24)
[Ahx9-20]-NPY 74 (322) 108 (20) 29 (36)
[Ahx9-17]-NPY 13 (57) 45 (8) 11 (14)
hPP >1000 (>4348) >1000 (>25000) 0.04 (0.007) 24 (30)
[Ahx5-24]-hPP >500 (>2174) >1000 (>25000) 144 (26) >1000 (>1250)
[Ahx5-20]-hPP >1500 (>6522) >1000 (>25000) 216 (39) >7000 (>8750)
[Y5-20]-hPP >500 (>2174) >1000 (>25000) 27 (5) >5000 (>6250)