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. 2018 Sep 17;9:140–150. doi: 10.1016/j.ynstr.2018.09.004

Table 1.

Examples of animal models of pre- and perinatal stress and human analogs.

Name Description Human Analog
Prenatal substance exposure Injection of substance (e.g., cocaine, morphine) into mother Prenatal substance exposure
Synthetic GC exposure Injection of synthetic glucocorticoid into mother Glucocorticoid use during pregnancy
Food restriction paradigm Restrict mother access to food Malnutrition
Restraint and immobilization stress paradigm Mother kept in cylindrical tube or restrained with adhesive tape Prenatal anxiety
Immune activation synthetic double strand RNA polyriboinosinic-polyribocytidilic acid (poly I:C) administered into mother Prenatal viral infection
Maternal separation Offspring exposed to maternal absence during first postnatal weeks Postnatal neglect