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Primary endpoint CNS objective response rate at 12 weeks*.
| Phase Ib (n = 5) | Phase II (n = 6) | Total (n = 11) | |
|---|---|---|---|
| Objective response rate, n (%) | 2 (40.0%) | 1 (16.7%) | 3 (27.3%) |
| Complete response | 0 | 0 | 0 |
| Partial response | 2 | 1 | 3 |
Evaluable population included eligible patients who received four cycles of treatment and underwent imaging of the brain at week 12.
CNS, central nervous system.
