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. Author manuscript; available in PMC: 2020 Feb 10.
Published in final edited form as: Sci Total Environ. 2018 Aug 29;650(Pt 1):1131–1140. doi: 10.1016/j.scitotenv.2018.08.356

Table 2.

Weighted distributions of plasma inflammatory biomarkers by study visit of sample collection during pregnancy in the LIFECODES cohort (N = 482 subjects).

Plasma inflammatory biomarker Visit N samples Overall % > LOD Geometric mean (geometric SD) Select percentiles
25 50 75 90 95
C-reactive protein (μg/mL) Total 1585 99.9% 5.72 (2.82) 2.82 5.26 11.0 24.0 34.4
1 417 4.83 (3.10) 2.22 4.16 9.27 23.9 38.3
2 403 6.50 (2.74) 3.13 5.93 13.9 27.4 37.4
3 387 6.22 (2.73) 3.24 6.06 12.8 23.9 34.4
4 378 5.53 (2.63) 2.99 5.36 9.41 21.3 29.3
IL 1β (pg/mL) Total 1585 78.0% 0.29 (3.43) 0.14 0.26 0.49 1.12 2.80
1 417 0.32 (3.37) 0.16 0.28 0.52 1.24 3.14
2 403 0.31 (3.31) 0.15 0.27 0.47 1.18 2.68
3 387 0.27 (3.47) 0.13 0.23 0.50 1.05 2.66
4 378 0.27 (3.54) 0.12 0.24 0.49 1.05 2.10
IL 6 (pg/mL) Total 1585 97.9% 1.48 (3.19) 0.81 1.33 2.35 5.16 11.8
1 417 1.55 (3.50) 0.80 1.34 2.51 7.00 14.9
2 403 1.35 (3.29) 0.74 1.21 2.16 4.86 10.9
3 387 1.34 (3.03) 0.80 1.24 2.17 4.17 9.28
4 378 1.70 (2.90) 0.96 1.54 2.53 5.80 11.9
IL 10 (pg/mL) Total 1585 99.9% 13.6 (2.56) 8.98 13.2 19.4 31.5 56.0
1 417 13.5 (2.78) 8.76 13.0 20.2 30.6 58.8
2 403 13.9 (2.51) 9.16 13.3 19.4 33.0 52.6
3 387 13.4 (2.41) 9.03 13.1 18.9 30.3 55.4
4 378 13.7 (2.54) 8.92 13.5 18.9 30.6 59.7
TNF α (pg/mL) Total 1585 99.9% 3.02 (1.83) 2.19 2.99 4.25 5.92 7.21
1 417 2.87 (1.84) 2.07 2.91 4.07 5.63 6.92
2 403 3.06 (1.83) 2.25 2.97 4.32 5.93 7.21
3 387 2.95 (1.78) 2.19 2.98 4.07 5.78 6.69
4 378 3.23 (1.84) 2.23 3.28 4.60 6.27 8.01

Abbreviations: Limit of detection (LOD); Interleukin 1β (IL 1β); Interleukin 6 (IL 6); Interleukin 10 (IL 10); Tumor necrosis factor α (TNF α).