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129SvEv female cells were not rejected in C57BL/6 female mice lacking a diverse natural IgM antibody repertoire or Batf3+ DCs. Schematic diagram illustrates experimental design. At Day 20, CD45.1 female 129/BL6 cells were recalled in CD45.2 IghelMD4 (Ighel) and Batf3−/− female mice compared with WT female mice, where complete rejection of 129/BL6 cells occurred. Flow plot represents n = 8 mice per group.
