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Inhibitory effect of concentration-relaxation curve on the phenylephrine-induced contraction with inhibitors L-NA 10μM (a), ODQ 10μM (a), TEA 1mM (b), and indomethacin 10μM (c) preincubated 30 minutes prior to phenylephrine. The relaxation response is expressed as the percentage relaxation of the phenylephrine-induced contraction (100% represent complete relaxation). Values are the mean ± SEM (n=5). ∗P<0.05, ∗∗P<0.01, and ∗∗∗P<0.001, significant differences compared with control.
