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. 2018 Nov 15;15:320. doi: 10.1186/s12974-018-1358-3

Table 3.

Relative mRNA levels of inflammatory mediators in DRG tissues

Gene CFA Saline + CFA EM-1 + CFA EM-2 + CFA
IL-1β 2.46 ± 0.70 3.67 ± 0.61* 1.08 ± 0.16 # 2.33 ± 0.57
IL-10 0.33 ± 0.11** 0.51 ± 0.13* 0.80 ± 0.12 0.77 ± 0.23
TNF-α 2.84 ± 0.41* 2.07 ± 0.60 1.41 ± 0.51 1.21 ± 0.08
CCL2 2.51 ± 0.63 2.91 ± 0.38* 1.25 ± 0.37 1.97 ± 0.61
CCL3 2.20 ± 0.44** 3.03 ± 0.34** 1.21 ± 0.35 2.58 ± 0.63

Inflammatory mediators mRNA levels are assessed by RT-PCR assay and normalized to GAPDH-expression

*P < 0.05 and **P < 0.01 indicates significant differences compared with Control samples according to one-way ANOVA followed by Bonferroni post-hoc analysis

#P < 0.05 indicates significant differences compared with Saline + CFA samples according to one-way ANOVA followed by Bonferroni post-hoc analysis