Table 3.
Odds ratio and 95% confidence interval for cardiometabolic risk factors: the CASPIAN-V study
| Variable | Model | High TC | High LDL | MetS | Low HDL | Overweight | Abdominal obesity | Obesity | High FBS | High TG | High BP |
|---|---|---|---|---|---|---|---|---|---|---|---|
| OR (95%CI) | OR (95%CI) | OR (95%CI) | OR (95%CI) | OR (95%CI) | OR (95%CI) | OR (95%CI) | OR (95%CI) | OR (95%CI) | OR (95%CI) | ||
| Non-HDL-C (mg/dl) | Model I | 1.19 (1.17,1.22)* |
1.19 (1.17,1.20)* |
1.01 (1.00,1.01)* |
0.99 (0.99,0.99)* |
1.00 (0.99,1.00) |
1.00 (0.99,1.00) |
1.00 (0.99,1.00) |
1.00 (1.00,1.01) |
1.03 (1.03,1.03)* |
0.99 (0.99,1.00) |
| Model II | 1.19 (1.16,1.22)* |
1.19 (1.17,1.21)* |
1.01 (1.00, 1.01)* |
0.99 (0.99,0.99)* |
1.00 (0.99,1.00) |
1.00 (0.99,1.00) |
1.00 (0.99,1.00) |
1.00 (.99,1.01) |
1.03 (1.02,1.03)* |
0.99 (0.99,1.00) |
|
| Model III | 1.19 (1.16,1.22)* |
1.19 (1.17,1.21)* |
1.01 (1.00, 1.01)* |
0.99 (0.99,0.99)* |
– | – | – | 1.00 (.99,1.01) |
1.03 (1.02,1.03)* |
0.99 (0.99,1.01) |
|
| Diff-C (mg/dl) | Model I | 1.07 (1.06,1.08)* |
1.02 (1.01,1.02)* |
1.07 (1.06,1.09)* | 1.04 (1.03,1.05)* |
1.01 (1.00,1.02)* |
1.00 (0.99,1.01) |
1.00 (0.99,1.01) |
1.04 (1.02,1.05)* |
1.02 (1.01,1.02)* |
1.00 (0.98,1.01) |
| Model II | 1.07 (1.06,1.09)* |
1.02 (1.01,1.03)* |
1.08 (1.07,1.01)* |
1.04 (1.04,1.05)* |
1.01 (1.00,1.02)* |
1.00 (0.99,1.01) |
1.00 (0.99,1.01) |
1.03 (1.02,1.05)* |
1.03 (1.02,1.04)* |
1.00 (0.99,1.01) |
|
| Model III | 1.07 (1.06,1.09)* |
1.02 (1.01,1.03)* |
1.08 (1.07, 1.10)* |
1.04 (1.04,1.05)* |
– | – | – | 1.03 (1.02,1.05)* |
1.02 (1.01,1.03)* |
1.00 (0.98,1.01) |
|
| Atherogenic index | Model I | 1.36 (1.26,1.46)* |
1.02 (0.96,1.08) |
1.8 (1.7, 2.00)* |
2.43 (2.25,2.63)* |
1.08 (1.00,1.16)* |
1.00 (0.95,1.06) |
1.03 (0.95,1.10) |
1.29 (1.19,1.40)* |
38.69 (29.85,50.14)* |
1.00 (0.92,1.08) |
| Model II | 1.34 (1.24,1.46)* |
1.03 (0.96,1.10) |
1.9 (1.7, 2.14)* |
2.51 (2.30,2.73)* |
1.07 (0.98,1.15) |
1.01 (0.95,1.08) |
1.03 (0.95,1.12) |
1.29 (1.18,1.41)* |
40.33 (30.45,53.43)* |
1.02 (0.94,1.11) |
|
| Model III | 1.35 (1.24,1.47)* |
1.03 (0.96,1.10) |
1.9 (1.8, 2.19)* |
2.50 (2.30,2.72)* |
– | – | – | 1.28 (1.17,1.40)* |
40.26 (30.36,53.40)* |
1.00 (0.92,1.09) |
* Statistically significant, BP blood pressure, TG triglycerides, FBG fasting blood glucose, HDL-C high-density lipoprotein-cholesterol, TC total cholesterol, LDL-C low-density lipoprotein cholesterol;
overweight: BMI; 85th–95th; obesity, BMI > 95th; low HDL: < 40 mg/dL (except in boys 15–19 y old, that cut-off was < 45 mg/dL); high LDL: > 110 mg/dL; high TG: 100 mg/dL; high TC: > 200 mg/dL; elevated FBS > 100 mg/dL; high blood pressure: > 90th (adjusted by age, sex, height); Non–HDL-C concentration was calculated by subtracting HDL-C value from total cholesterol concentration. Diff-C was defined as the difference between total amount of non-HDL cholesterol and LDL-C (Diff-C = [non-HDL-C]-[LDL-C]). Atherogenic index as the ratio between TG and HDL-C concentrations
Model 1: crude model
Model 2: adjusted for age, sex, living area, screen time, SES and physical activity
Model3: additionally adjusted for BMI except for overweight, obesity and abdominal obesity