Table 4.
Receiver operator curve for Non–High-Density lipoprotein fractions for identifying children with MetS
| Variable | Age-sex group | Cut-off points (95% CI) | Sensitivity (95% CI) | Specificity (95% CI) | AUC |
|---|---|---|---|---|---|
| Non-HDL-C (mg/dl) | 7–10 y | ||||
| Boy | 163 (96.29, 227.70) |
0.69 (0.585, 0.807) |
0.73 (0.48, 0.97) |
0.71 | |
| Girl | 104.5 (88.21, 119.78) |
0.71 (0.47, 0.95) |
0.50 (0.28, 0.70) |
0.60 | |
| Total | 104.5 (73.99, 134.00) |
0.60 (0.28, 0.91) |
0.50 (0.14, 0.85) |
0.55 | |
| 11–14 y | |||||
| Boy | 119.5 (107.00,130.99) |
0.54 (0.34,0.74) |
0.73 (0.59,0.85) |
0.64 | |
| Girl | 116.5 (77.57,154.42) |
0.49 (0.10, 0.86) |
0.65 (0.21, 1.07) |
0.57 | |
| Total | 116.5 (111.38, 120.61) |
0.53 (0.37, 0.68) |
0.67 (0.57, 0.76) |
0.60 | |
| 15–18 y | |||||
| Boy | 101.5 (81.67,120.32) |
0.91 (0.66,1.16) |
0.51 (0.27,0.73) |
0.71 | |
| Girl | 115.5 (75.49, 154.50) |
0.54 (0.07, 1.00) |
0.64 (0.14, 1.14) |
0.59 | |
| Total | 104.5 (83.66, 124.33) |
0.79 (0.52, 1.06) |
0.52 (0.25, 0.78) |
0.65 | |
| 7-18y | |||||
| Boy | 119.5 (103.37, 134.62) |
0.49 (0.26, 0.71) |
0.73 (0.50, 0.95) |
0.61 | |
| Girl | 115.5 (88.58, 141.41) |
0.49 (0.18, 0.78) |
0.64 (0.25, 1.01) |
0.56 | |
| Total | 120.5 (105.33, 134.66) |
0.44 (0.22, 0.65) |
0.73 (0.52, 0.93) |
0.58 | |
| Diff-C (mg/dl) | 7–10 y | ||||
| Boy | 19.9 (17.47, 22.12) |
0.78 (0.60, 0.95) |
0.78 (0.72, 0.83) |
0.78 | |
| Girl | 20.7 (15.94, 25.25) |
0.89 (0.75, 1.00) |
0.78 (0.66, 0.89) |
0.84 | |
| Total | 19.9 (18.88,20.71) |
0.84 (0.73,0.93) |
0.77 (0.72,0.81) |
0.80 | |
| 11–14 y | |||||
| Boy | 19.9 (18.26, 21.33) |
0.83 (0.71, 0.93) |
0.77 (0.72, 0.81) |
0.80 | |
| Girl | 19.9 (18.18, 21.41) |
0.82 (0.69, 0.94) |
0.73 (0.64, 0.82) |
0.78 | |
| Total | 19.9 (18.41, 21.18) |
0.82 (0.74,0.90) |
0.75 (0.71,0.78) |
0.79 | |
| 15–18 y | |||||
| Boy | 19.9 (18.05, 21.54) |
0.91 (0.83, 0.99) |
0.74 (0.67, 0.80) |
0.83 | |
| Girl | 20.5 (15.45, 25.34) |
0.92 (0.75, 1.08) |
0.76 (0.68, 0.84) |
0.84 | |
| Total | 19.9 (19.16,20.43) |
0.92 (0.84,0.99) |
0.74 (0.70,0.77) |
0.83 | |
| 7–18 y | |||||
| Boy | 19.9 (19.26,20.33) |
0.84 (0.76,0.91) |
0.76 (0.73,0.79) |
0.80 | |
| Girl | 19.9 (19.37,20.22) |
0.86 (0.78,0.93) |
0.74 (0.70,0.78) |
0.80 | |
| Total | 19.9 (19.76, 19.83) |
0.85 (0.79,0.90) |
0.75 (0.74,0.76) |
0.80 | |
| Atherogenic index | 7–10 y | ||||
| Boy | 2.53 (1.83,3.23) |
0.70 (0.52,0.88) |
0.83 (0.70,0.95) |
0.77 | |
| Girl | 2.57 (2.03,3.10) |
0.93 (0.83,1.02) |
0.81 (0.69,0.92) |
0.87 | |
| Total | 2.53 (2.10,2.96) |
0.82 (0.72,0.90) |
0.81 (0.71,0.91) |
0.82 | |
| 11–14 y | |||||
| Boy | 2.58 (2.37,2.78) |
0.80 (0.70,0.90) |
0.82 (0.78,0.86) |
0.81 | |
| Girl | 2.54 (1.96,3.11) |
0.79 (0.65,0.93) |
0.77 (0.61,0.93) |
0.78 | |
| Total | 2.54 (2.25,2.83) |
0.80 (0.70,0.89) |
0.80 (0.72,0.87) |
0.80 | |
| 15–18 y | |||||
| Boy | 2.48 (2.04,2.91) |
0.89 (0.75,1.01) |
0.75 (0.65,0.83) |
0.82 | |
| Girl | 2.73 (2.24,3.22) |
0.92 (0.79,1.05) |
0.82 (0.75,0.88) |
0.87 | |
| Total | 2.48 (2.17,2.78) |
0.90 (0.79,.99) |
0.76 (0.69,0.82) |
0.83 | |
| 7–18 y | |||||
| Boy | 2.53 (2.35,2.71) |
0.80 (0.71,0.88) |
0.80 (0.76,0.83) |
0.80 | |
| Girl | 2.54 (2.19,2.89) |
0.86 (0.77,0.94) |
0.79 (0.71,0.86) |
0.83 | |
| Total | 2.53 (2.41,2.65) |
0.82 (0.76,0.88) |
0.79 (0.76,0.82) |
0.81 | |
CI confidence interval, AUC area under curve, shown as percentage
Non–HDL-C concentration was calculated by subtracting HDL-C value from total cholesterol concentration. Diff-C was defined as the difference between total amount of non-HDL cholesterol and LDL-C (Diff-C = [non-HDL-C]-[LDL-C]). Atherogenic index as the ratio between TG and HDL-C concentrations