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. 2018 Nov 14;17:256. doi: 10.1186/s12944-018-0901-7

Table 3.

Correlation of PPARα and its target genes with main clinical parameters in OF group

OF group SLC PDK4 PPARα CPT1B ACAA2 ACADVL CPT1A
AC, Pearson Correlation .112 −.436* −.383 −.411* −.131 .303 −.403*
Significant (unilateral) .324 .031 .053 .040 .297 .104 .044
BMI, Pearson Correlation .360 −.532** −.577** −.512* −.499* .450* −.549**
Significant (unilateral) .065 .010 .005 .012 .015 .027 .007
SBP, Pearson Correlation −.065 −.204 −.175 −.233 −.035 −.051 −.285
Significant (unilateral) .396 .201 .236 .168 .443 .417 .118
DBP, Pearson Correlation .245 −.573** −.561** −.628** −.395* .270 −.677**
Significant (unilateral) .156 .005 .006 .002 .047 .132 .001
ALT, Pearson Correlation −.373 −.486* −.365 −.387 −.228 −.177 −.382
Significant (unilateral) .058 .018 .062 .051 .173 .235 .053
GLU, Pearson Correlation −.264 .425* .484* .388 .382 −.530** .385
Significant (unilateral) .137 .035 .018 .050 .053 .010 .052
INS, Pearson Correlation −.432* .224 .422* .291 .441* −.349 .326
Significant (unilateral) .032 .178 .036 .114 .029 .071 .086
HOMA
-IR,
Pearson Correlation −.444* .342 .546** .377 .538** −.445* .424*
Significant (unilateral) .028 .076 .008 .056 .009 .028 .035

In the OF group, the correlation between PPARα target genes and primary clinical parameters were determined using the Spearman rank test (*p < 0.05,**p < 0.01)

AC Abdominal circumference, ALT Alanine transaminase, BMI body mass index, DBP diastolic blood press, Glu Glucose, HOMA-IR Homeostasis model assessment of insulin resistance, INS Insulin, SBP Systolic blood press