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Effects of CGRP8–37, PD98059, SB203580, and SP600125 on EPC proliferation and apoptosis. Quantitative analysis of the proliferative target genes cyclin D1 and cyclin E (a, b) or apoptotic target genes caspase-3, caspase-8, caspase-9, Bax and Bcl-2 (d-h). The protein levels of cleaved caspase-3 were evaluated by Western blot (c). # p < 0.05 compared with the CGRP-only group
