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. 2018 Nov 8;9:1283. doi: 10.3389/fphar.2018.01283

FIGURE 2.

FIGURE 2

Absorption-enhancement mechanisms mediated by bile acids: (1) solubilization of lipophilic drugs; (2) effects on biological membranes – increasing fluidity, opening tight junctions, formation of reverse micelles, membranolytic effect, modulation of transport proteins; (3) improvement of chemical stability of drugs.