Table 2.

miRNA levels in the tissues of control and diseased veins

miRNAs	Control	Disease	P Value	Nonsignificant	Significant
(RQ)	n=10	n=10		n=5	n=5
MiR-21	0.74 (0.27–2.11)	7.29 (3.76–15.2)	<0.001	3.77 (2.80–4.74)	14.9 (10.6–21.2)
MiR-130a	0.47 (0.17–0.99)	1.84 (0.36–6.55)	0.06	0.38 (0.26–0.63)	5.83 (4.21–14.6)
MiR-221	0.89 (1.14–2.63)	14.1 (3.04–60.5)	0.02	3.72 (0.99–6.44)	56.7 (33.8–79.7)
MiR-222	1.53 (1.18–2.56)	10.4 (4.46–24.9)	0.02	5.62 (0.86–10.4)	22.9 (13.6–32.2)
MiR-133	2.57 (2.02–3.02)	0.58 (0.15–1.00)	<0.001	0.91 (0.48–2.24)	0.22 (0.11–0.58)
MiR-145	1.13 (0.93–1.63)	0.09 (0.06–0.80)	0.02	0.75 (0.07–1.94)	0.07 (0.05–0.08)

The miRNA levels in the diseased veins were classified as significant or nonsignificant stenosis. Values are median (interquartile range). miRNA, microRNA; RQ, relative quantities, the relative expression level of miRNAs was determined by the cycle number via quantitative real-time PCR, normalized to U6 expression.