Table 1.
Baseline characteristics of hospitalized participants with acute kidney disease in the Yale biopsy cohort
| Characteristic | Participants (n=159) |
|---|---|
| Demographics | |
| Age, yr | 59 (47, 68) |
| Female | 68 (43%) |
| Black race | 37 (23%) |
| Diabetes | 63 (40%) |
| Hypertension | 106 (67%) |
| Cirrhosis | 20 (13%) |
| CKD | 91 (62%) |
| BMI, kg/m2 | 28 (25, 33) |
| BMI>35 kg/m2 | 32 (20%) |
| Baseline laboratory features | |
| Baseline creatinine, mg/dl | 1.3 (0.9, 1.9) |
| Baseline GFR, ml/min | 46 (30, 74) |
| Baseline protein-to-creatinine ratio, mg/mg | 2.0 (0.6, 5.1) |
| Dipstick protein ≥3 | 111 (73%) |
| Features at biopsy | |
| AKI | 132 (83%) |
| Stage 1 | 80 (51%) |
| Stage 2 or higher | 42 (27%) |
| Dialysis | 16 (10%) |
| Acute kidney disease (excluding AKI) | 27 (17%) |
| Creatinine, mg/dl | 4.4 (3.2, 6.8) |
| BUN, mg/dl | 52 (35, 76) |
| BUN>60 mg/dl | 65 (41%) |
| Hemoglobin, g/dl | 9.2 (8.0, 10.2) |
| Hemoglobin<10 g/dl | 116 (73%) |
| Platelets per mm3 | 202 (142, 278) |
| Location | |
| Floor | 143 (90%) |
| Intensive care unit | 16 (10%) |
| Campus | |
| York St. | 128 (81%) |
| St. Raphael’s | 31 (19%) |
| Procedural factors | |
| Passes | 3 (2, 3) |
| Fellow as primary proceduralist (versus Attending) | 103 (65%) |
| Nephrology (versus Radiology) | 104 (65%) |
| Needle gauge 16 (versus 18) | 88 (55%) |
| Ultrasound-guided (versus CT) | 118 (74%) |
| Primary histologic diagnosis | |
| Acute interstitial nephritis | 24 (15%) |
| Acute tubular necrosis | 30 (19%) |
| Diabetes | 28 (18%) |
| Glomerular disease | 37 (23%) |
| Arterionephrosclerosis | 17 (11%) |
| Other | 23 (14%) |
N (%) or median (interquartile range) seen. BMI, body mass index; CT, computerized tomography.