Table 5.
Estimated Coefficient of Variation (wCV) as a Function of Nodule Characteristics and Reconstructed Slice Thickness
| Parameter | Value | Slice Thickness 0.8 mm (%) | Slice Thickness 5 mm* (%) | All (%) |
|---|---|---|---|---|
| Shape | Spherical | 3.69 | 4.54 | 4.11 |
| [2.60, 4.77] | [3.20, 5.87] | [3.28, 4.94] | ||
| Elliptical | 5.19 | 7.82 | 6.50 | |
| [2.09, 8.28] | [3.72, 11.91] | [3.94, 9.07] | ||
| Lobulated | 7.89 | 6.28 | 7.08 | |
| [1.49, 14.29] | [2.54, 10.01] | [4.94, 10.96] | ||
| Spiculated | 4.77 | 7.35 | 6.06 | |
| [1.99, 7.54] | [2.45, 12.26] | [3.23, 8.89] | ||
| Irregular | 6.47 | 4.48 | 5.48 | |
| [3.08, 9.85] | [0.61, 8.35] | [2.90, 8.05] | ||
| Density (HU) | −630* | 3.83 | 4.16 | 4.00 |
| [2.89, 4.77] | [3.07, 5.25] | [3.24, 4.76] | ||
| −300 | 8.80 | 3.75 | 6.27 | |
| [4.16, 13.44] | [0.70, 7.43] | [3.01, 9.54] | ||
| −10 | 6.81 | 7.64 | 7.23 | |
| [3.07, 10.55] | [4.60, 10.68] | [4.66, 9.79] | ||
| 20 | 6.11 | 6.00 | 6.06 | |
| [1.91, 10.32] | [−0.68, 12.69] | [2/17, 9.94] | ||
| 100 | 3.76 | 5.51 | 4.64 | |
| [1.49, 6.03] | [1.99, 9.04] | [2.37, 6.91] | ||
| Size (mm) | 5* | 13.10 | 12.35 | 12.73 |
| [4.46, 21.74] | [ 8.34, 16.36] | [7.89, 17.55] | ||
| 8* | 7.56 | 7.41 | 7.49 | |
| [3.87, 11.25] | [4.08, 10.74] | [4.89, 10.08] | ||
| 10 | 4.70 | 6.47 | 5.59 | |
| [3.14, 6.27] | [4.03, 8.92] | [4.12, 7.05] | ||
| 12 | 6.11 | 6.00 | 6.06 | |
| [2.46, 9.77] | [−0.27, 12.29] | [2.63, 9.48] | ||
| 20 | 2.30 | 3.53 | 2.91 | |
| [0.95, 3.65] | [0.71, 6.34] | [1.40, 4.43] | ||
| 40 | 0.82 | 1.34 | 1.08 | |
| [0.32, 1.32] | [0.63, 2.04] | [0.65, 1.51] | ||
| All | 5.33 | 6.18 | 5.76 | |
| [4.08, 6.59] | [5.15, 7.21] | [4.93, 6.59] |
*
Criteria that do not meet the Quantitative Imaging Biomarker Alliance (QIBA) Profile.