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. 2018 Sep 20;3(18):e96902. doi: 10.1172/jci.insight.96902

Figure 4. BLT1-expressing macrophages are involved in the pathogenesis of laser-induced CNV.

Figure 4

(A and B) The effect of clodronate liposome–mediated macrophage depletion (indicated as Clodronate, filled circles) on CNV volume in aged BLT1-WT and BLT1-KO mice (>20 weeks old). Control refers to control liposomes (open circles). n = 4–7 mice per group. Scale bar: 100 μm. (B) *P < 0.05; **P < 0.01 (1-way ANOVA with Newman-Keuls post hoc test). Results are representative of at least 2 independent experiments.