Skip to main content
. 2018 Sep 20;3(18):e96902. doi: 10.1172/jci.insight.96902

Figure 8. M2 macrophage-dependent CNV development requires BLT1.

Figure 8

Images of iB4 staining (A) and CNV volume (B) in the RPE-choroid of recipient mice that received M0-, M2-, and M1-BMDMs from aged BLT1-WT (open circles) or BLT1-KO (filled circles) mice (>20 weeks old). n = 6–8 mice per group. (C and D) H&E staining of the laser-injured retinas of recipient mice receiving M2-BMDMs from BLT1-WT or BLT1-KO mice (>20 weeks old). Yellow dotted lines show the lesion area. n = 4 per group. Scale bar: 100 μm (A and C). (B and D) *P < 0.05 (1-way ANOVA with Bonferroni’s post hoc test [B] and Student’s t test [D]). Results are representative of at least 2 independent experiments.