Table 1. Image acquisition and reconstruction parameters of the rat proximal tibiae for the three doses groups.

	0.83 Gy	1.65 Gy	2.47 Gy
Scanning parameters
Voxel size (μm)	18	18	9
Voltage (kV)	65	65	65
Current (μA)	385	385	385
Rotation step (over 180°)	0.65°	0.50°	0.65°
Exposure time (ms)	350	350	1140
Frames averaged per projection	1	2	1
Filter	AL 1mm	AL 1mm	AL 1mm
Approximate scan time (min)	6	11	17
Reconstruction Parameters
Filter	Gaussian	Gaussian	Gaussian
Smoothing kernel	1	1	1
Ring artifact reduction	4	4	4
Beam hardening correction (%)	10	10	10
Attenuation coefficient	0.000–0.049	0.000–0.049	0.000–0.049
Analysis Parameters
Thresholding	Global, 65	Global, 65	Global, 65

All micro-CT scans were obtained using the SkyScan 1176 model, Bruker-microCT.