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. 2018 Oct 18;3(20):e121521. doi: 10.1172/jci.insight.121521

Figure 3. Loss of Ent1 does not protect the colonic mucosa during experimental colitis.

Figure 3

Ent1-deficient mice (Ent1–/–) or C57BL/6 WT controls (Ent1+/+) matched by sex, age, and weight were exposed to water or DSS. (A) Weight measurements were obtained for each group of mice and are displayed as percentage of body weight on day 0. (B) Following sacrifice, colons were harvested and measured. (C) Representative histological sections from whole colon harvested on day 7 after DSS (scale bars: 200 μm; images acquired at ×10). Results of 3 independent experiments are shown as mean ± SEM (n = 6–24 mice/group). Two-way ANOVA with post hoc Bonferroni’s t test was used to determine statistical weight change. Two-way ANOVA with post hoc Tukey’s multiple comparison test was used to determine statistical colon length change. P < 0.05.