Figure 6.

MAPK1 played a role in HCC cell proliferation through miR‐217 regulation. (A) MTT assay showed that sh‐MAPK1 could largely reverse the accelerating effects of anti‐miR‐217 on proliferation of HepG2 cells while MAPK1 abrogated the suppressive effects of miR‐217 mimics on proliferation of Huh‐7 cells. (B) BrdU staining assay demonstrated HCC cell proliferation ability was enhanced by anti‐miR‐217 or MAPK1 while it was weakened by sh‐MAPK1 or miR‐217. **P < 0.01, compared with NC group. ^## P < 0.01, compared with anti‐miR‐217+ sh‐MAPK1/miR‐217+MAPK1 group