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. 2018 Sep 25;22(12):6213–6227. doi: 10.1111/jcmm.13908

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© 2018 The Authors. Journal of Cellular and Molecular Medicine published by John Wiley & Sons Ltd and Foundation for Cellular and Molecular Medicine.

This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.

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Deguelin suppresses tumour growth in vivo. A and B, Deguelin significantly inhibited tumour growth in H1299 (A) and A549 (B) xenograft mouse models. C and D, The tumour weight from vehicle‐ and deguelin‐treated group was measured in H1299 (C) and A549 (D) xenograft mouse models. E, Immunohistochemical staining examination of Ki67, Bmi1, Noxa, and cleaved caspase‐3 in H1299 tumour sections from the mice of the vehicle‐ or deguelin‐treated group. All panels are of the same magnification (**P < 0.01, ***P < 0.001, vs vehicle‐treated group)