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. 2018 Oct 15;22(12):6294–6303. doi: 10.1111/jcmm.13921

Figure 5.

Figure 5

FGF1 treatment suppressed diabetes‐induced ER stress and up‐regulation of Bax in kidney. A, The protein expression of p‐PERK, p‐IRE1α, ATF6, GRP78 and CHOP of kidney from db/m, db/db and db+FGF1 group; B, Intensities of p‐IRE1α normalized to IRE1α, p‐PERK, ATF6, CHOP and GRP78 normalized to GADPH; C, The protein expression of Bax of kidney from db/m, db/db and db+FGF1 group; D and E, Immunohistochemical staining of CHOP of kidney from db/m, db/db and db+FGF1 group (scale bars = 30 μm). All data are presented as the mean ± SEM, n = 3. *P < 0.05 vs the db/m group and db+FGF1 group