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. 2018 Oct 15;22(12):6294–6303. doi: 10.1111/jcmm.13921

Figure 6.

Figure 6

A Schematic showing the effect of cellular stress during FGF1 treatment for Diabetic nephropathy. FGF1 treatment blocked hyperglycemia‐induced oxidative stress though NOX2‐ROS‐Nrf2 signalling, and elevated ER stress in kidney, which ameliorated interstitial fibrosis and glomerular damage