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Effect of the RIPK1 inhibitor necrostatin‐1 on (A and B) apoptosis and (C) caspase activity. A and B, Apoptotic rate of THP‐1 cells determined by flow cytometry. B, Activities of caspase‐3 and caspase‐8. The cells were pretreated with necrostatin‐1 (10 μM) and then incubated with Tp92 (5 μg/mL) for 12 hours. *P < 0.05 compared with the Tp92 group
