Fig. 6.

MiR-1246 inhibits BFR-L1 cell apoptosis. a Flow cytometry analysis of BFR-L1 cell apoptosis. Lower left quadrant represents intact cells (FITC−/PI−), lower right quadrant represents early apoptotic cells (FITC+/PI−), upper right quadrant represents late apoptotic cells (FITC−/PI+), upper left quadrant represents necrotic cells (FITC+/PI+). b Cell apoptosis after mimics or NC transfection in BFR-L1 cells by DAPI and FITC/PI staining. Apoptosis cells showed fragmentation of the nuclei. Empty represents cells exposed in 42 °C, without transfection mimics or NC