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Intrinsic structural heterogeneity of domain D5. Schematic representation of the D5OB and D5res-α conformational states within the rS1 constructs (A) rS1-D5, (B) rS1-D45 and (C) rS1-D345. The populations are displayed in the scheme. (D) D5 populations in the absence and presence of Asw-42.
