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. 2018 Oct 5;46(20):10709–10723. doi: 10.1093/nar/gky853

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© The Author(s) 2018. Published by Oxford University Press on behalf of Nucleic Acids Research.

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com

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Figure 6. — Small RNA sequence variation caused by variability in the position of the first cut. (A–P) miRNAs for which the biogenesis is base-to-loop are displayed on the left panels (turquoise bars) (A–H), while loop-to-base miRNAs are displayed on the right panels (blue bars) (I–P). (A) miR165a, (B) miR168ab, (C) miR390ab, (D) miR396a (E) miR398bc (F) miR173, (G) miR824, and (H) average base-to-loop miRNA; (I) miR156a-f, (J) miR157ab, (K) miR157c, (L) miR160a-c, (M) miR408, (N) miR400, (O) miR825, (P) average loop-to-base miRNA. The miRNA sequence is indicated below each graph. The bar shows the frequency of the small RNAs ending at that position. For the average miRNA (H and P) the bases are depicted as squares.