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. 2018 Jul 11;37(46):6041–6053. doi: 10.1038/s41388-018-0403-0

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© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 5 — MUC20 knockdown inhibits migration and invasion of PDAC cells co-cultured with PSCs. a MUC20 knockdown inhibited migration and invasion induced by pancreatic stellate cells (PSCs) in HPAC (upper) and HPAF-II (lower) cells. b MUC20 knockdown inhibited migration and invasion induced by PSC-conditioned medium. Cell migration and invasion were analysed by Transwell migration and Matrigel invasion assay, respectively. The left panel shows representative images of migrated and invaded cells. The right panel shows statistics of cell migration and invasion. Scale bars indicate 1 mm. Data are presented as mean (n = 3) ± SD. *P < 0.05; **P < 0.01