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Mappability of differentially methylated regions of mice mammary basal and luminal alveolar tissues. (A) Single-read and (B) multi-read mappability of differentially methylated regions. (C) A differentially methylated region identified with 50-nt sequencing reads that are not uniquely mappable (purple). None of the sequencing reads that overlap this differentially methylated region uniquely map to the bisulfite-converted genome, although they all map uniquely to the unmodified genome.
