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. 2018 Sep 12;46(20):10946–10968. doi: 10.1093/nar/gky762

Table 1.

Nucleotide composition by structural context in the non-redundant bacterial and mmt SSU rRNA alignments

Nucleotide composition in bacterial alignment (%)
Structural Context G C A U Total
Helix 11.4 8.8 5.6 7.4 33.2
Flanking 11.0 8.6 3.3 4.7 27.6
Loop 9.4 5.1 16.2 8.5 39.2
Total 31.7 22.6 25.2 20.6 100.0
Standard deviation of base composition across sequences in the alignment 1.54 1.42 1.55 1.40
Nucleotide composition in mmt alignment (%)
Structural Context G C A U Total
Helix 5.9 5.7 7.3 7.5 26.5
Flanking 8.2 8.3 6.7 6.1 29.3
Loop 4.3 8.7 21.5 9.6 44.2
Total 18.5 22.7 35.6 23.3 100.0
Standard deviation of base composition across sequences in the alignment 1.15 1.60 1.46 1.55

The structural context is classified as Helix (for those nts within a helix), Flanking (for those nts at the ends of helices), and Loop (for internal or hairpin loops). The standard deviation is obtained, for example, by calculating the %G in each sequence of the alignment, and then calculating the standard deviation of those numbers.