Fig. 1. The PI3K/mTOR pathway is downregulated in the rd10 retina.

a Western blots of whole retinal phosphorylated Akt (p-Akt), p-mTOR, and p-PTEN from rd10 mice and age-matched C57BL/6 mice. β-actin levels were used as a loading control. b–d Densitometric analyses of the ratio of p-Akt (b), p-mTOR (c), and p-PTEN (d) to β-actin. Data are the mean±SD (n = 4). ns, not significant, *p < 0.05, **p < 0.01