Table 1.

Cox proportional hazard regression model

Univariate		Resected			Unresectable
		HR	95% CI	p-value	HR	95% CI	p-value
Age		1.01	0.97–1.04	0.73	1.02	0.99–1.05	0.203
Gender	Male	1			1
	Female	0.64	0.31–1.32	0.225	1.32	0.84–2.07	0.236
Stage	I	1
	II	2.37	0.56–10.01	0.242	1		0.022
	III	2.14	0.41–11.12	0.368	1.44	0.59–3.54	0.424
	IV	3.86	0.35–42.93	0.273	2.51	1.06–5.99	0.038
Tumor size	≤ 20 mm	1			1
	> 20 mm	2.01	0.83–4.92	0.124	25.36	0.37–1749	0.134
CA19–9	Low	1			1
	High	3.28	1.05–10.19	0.04	2.11	1.21–3.69	0.008
LNR		7.49	1.61–34.89	0.01	n/a	n/a	n/a
ADAM12	Low	1			1
	High	2.07	1.03–4.16	0.041	0.67	0.41–1.10	0.116

Univariate analysis for overall survival in PDAC patients (resected N = 58; unresectable N = 86). Dichotomization of resected patients by CA19-9 was at 415 kU/L, by ADAM12 at 316 pg/mL. Dichotomization of unresectable patients by CA19-9 was at 354 kU/L. LNR lymph node ratio