Table 1.
Characteristics of patients.
| Characteristic | Subgroup | Value |
|---|---|---|
| Age, mean (range) | Years | 58 (21–78) |
| Sex, n (%) | Male | 71 (35.9%) |
| Primary site, n (%) | Breast | 40 (20.2) |
| Gastric | 31 (15.7) | |
| Lung | 30 (15.2) | |
| Ovary | 22 (11.1) | |
| Sarcoma | 13 (6.6) | |
| Neuroendocrine | 10 (6.1) | |
| Bile duct | 9 (4.5) | |
| Thymic | 7 (3.1) | |
| Cervical | 5 (2.5) | |
| Urine body | 5 (2.5) | |
| Colon | 3 (1.5) | |
| Pancreas | 3 (1.5) | |
| Gene mutations, n | TP53 | 107 |
| BRCA2 | 24 | |
| NOTCH2 | 23 | |
| PIK3CA | 21 | |
| TSC1 | 21 | |
| RET | 19 | |
| ROS1 | 19 | |
| SETD2 | 17 | |
| ATM | 16 | |
| NOTCH1 | 16 | |
| PTCH1 | 16 | |
| APC | 15 | |
| KRAS | 15 | |
| STK11 | 15 | |
| ALK | 14 | |
| ABL1 | 13 | |
| ARID1A | 13 | |
| BRCA1 | 13 | |
| others | 388 | |
| gene Amplifications, copy number | MYC | 10 |
| ERBB2 | 9 | |
| CCND1 | 6 | |
| EGFR | 4 | |
| MDM2 | 4 | |
| FGFR1 | 2 | |
| NOTCH3 | 2 | |
| CD274 | 1 | |
| CDK4 | 1 | |
| IGF1R | 1 |