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. 2018 Dec;11(3):200–208. doi: 10.2174/1874471011666180502104524

Table 1.

Overview of clinical experience with 225Ac- and 213Bi-labeled compounds.

Cancer type Radioconjugate Patients References
Leukemia 213Bi-HuM195mAb 49 [38,39]
- 225Ac-HuM195mAb 36 [40]
Lymphoma 213Bi-anti-CD20-mAb 12 [41]
Melanoma 213Bi-9.2.27mAb 54 [42-44]
Bladder Cancer 213Bi-anti-EGFR-mAb 12 [32,45]
Glioma 213Bi-Substance P 68 [46-48]
- 225Ac-Substance P 19 [48]
Neuroendocrine tumors 213Bi-DOTATOC 25 [4]
- 225Ac-DOTATOC 39 [49]
Prostate cancer 225Ac-PSMA-617 190 [5,50,51]