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. 2018 Nov 15;8:16853. doi: 10.1038/s41598-018-35203-y

Table 1.

The 30 most up-regulated differentially expressed genes in the uterus of layers compared to non-layers.

Gene Name Gene Description Fold Change
OC-116 ovocleidin-116 174.00
OTOP2 otopetrin 2 15.11
TSKU tsukushi, small leucine rich proteoglycan 9.85
PRKG2 protein kinase, cGMP-dependent, type II 9.47
SGK1 serum/glucocorticoid regulated kinase 1 8.00
TC2N tandem C2 domains, nuclear 6.95
NEU4 sialidase 4 6.76
GADL1 glutamate decarboxylase like 1 6.62
FGF1 fibroblast growth factor 1 5.63
LYZ lysozyme (renal amyloidosis) 5.45
RUBCNL RUN and cysteine rich domain containing beclin 1 interacting protein like 5.09
GAL3ST2 galactose-3-O-sulfotransferase 2 4.92
WSCD2 WSC domain containing 2 4.76
NIPAL1 NIPA like domain containing 1 4.52
LOC427491 C2 calcium-dependent domain containing 4C-like 4.43
ROS1 ROS proto-oncogene 1, receptor tyrosine kinase 4.29
PHGDH phosphoglycerate dehydrogenase 4.21
SLC5A9 solute carrier family 5 member 9 4.17
FST follistatin 4.05
FXYD2 FXYD domain containing ion transport regulator 2 4.01
MCMDC2 minichromosome maintenance domain containing 2 3.97
ALDH1L2 aldehyde dehydrogenase 1 family member L2 3.87
DIO2 deiodinase, iodothyronine type II 3.87
ATP2B2 ATPase plasma membrane Ca2 + transporting 2 3.83
NPDC1 neural proliferation, differentiation and control 1 3.69
GNRHR gonadotropin-releasing hormone receptor 3.65
SRM spermidine synthase 3.64
OSTN osteocrin 3.63
NTN3 netrin 1 3.49
OVST ovostatin 3.45

Transcripts from uteri of layers and non-layers were aligned to chicken genome and mapped genes with at least 2-fold change difference and Benjamini Hochberg q-value < 0.05 were considered differentially expressed.