Table 2.
The 30 most down-regulated differentially expressed genes in the uterus of layers compared to non-layers.
| Gene Name | Gene Description | Fold Change |
|---|---|---|
| SMC2 | structural maintenance of chromosomes 2 | 8.9721 |
| RRM2 | ribonucleotide reductase regulatory subunit M2 | 7.6598 |
| CCNB3 | cyclin B3 | 7.4819 |
| ASPM | abnormal spindle microtubule assembly | 6.9292 |
| RACGAP1 | Rac GTPase activating protein 1 | 6.7528 |
| CDCA3 | Cell division cycle associated 3 | 6.5454 |
| CKAP2 | cytoskeleton-associated protein 2 | 6.529 |
| UBE2C | ubiquitin conjugating enzyme E2 U (putative) | 6.4307 |
| BRCA1 | breast cancer 1 | 6.3755 |
| KNTC1 | kinetochore associated 1 | 6.2464 |
| CENPE | centromere protein E | 6.2078 |
| TPX2 | TPX2, microtubule nucleation factor | 6.076 |
| BUB1 | BUB1 mitotic checkpoint serine/threonine kinase | 6.0022 |
| CKS1B | CDC28 protein kinase regulatory subunit 1B | 5.5194 |
| KIF11 | kinesin family member 11 | 5.4992 |
| NUSAP1 | nucleolar and spindle associated protein 1 | 5.4481 |
| ADAMTS18 | ADAM metallopeptidase with thrombospondin type 1 motif 18 | 5.4347 |
| DNA2 | DNA replication helicase/nuclease 2 | 5.4128 |
| NEK2 | NIMA related kinase 2 | 5.4027 |
| PLK1 | polo like kinase 1 | 5.2537 |
| CENPF | centromere protein F | 5.1474 |
| CIT | citron rho-interacting serine/threonine kinase | 5.1143 |
| MELK | maternal embryonic leucine zipper kinase | 4.9878 |
| KPNA2 | karyopherin subunit alpha 2 | 4.9424 |
| TOP2A | topoisomerase (DNA) II alpha | 4.9072 |
| TK1 | thymidine kinase 1 | 4.8336 |
| ECT2 | epithelial cell transforming 2 | 4.8087 |
| POLQ | DNA polymerase theta | 4.7944 |
| ARHGAP19 | Rho GTPase activating protein 19 | 4.7514 |
| PLK4 | polo like kinase 4 | 4.6305 |
Transcripts from uteri of layers and non-layers were aligned to chicken genome and mapped genes with at least 2-fold change difference and Benjamini Hochberg q-value < 0.05 were considered differentially expressed.