Table 2.
Correlations between the levels of autophagy-related proteins in the CSF and conventional CSF or clinical markers in patients with PD.
| LC3-B | Beclin-1 | ATG5 | LAMP-2 | |||||
|---|---|---|---|---|---|---|---|---|
| r | p-value | r | p-value | r | p-value | r | p-value | |
| α-synuclein (CSF) | 0.51 | <0.01 | −0.15 | NS | 0.17 | NS | 0.25 | NS |
| Total tau (CSF) | 0.51 | <0.01 | −0.27 | NS | 0.27 | NS | 0.20 | NS |
| P-tau (CSF) | 0.20 | NS | 0.30 | NS | 0.10 | NS | −0.34 | NS |
| Tau ratio (CSF) | −0.38 | <0.05 | 0.16 | NS | −0.07 | NS | −0.29 | NS |
PD: Parkinson’s disease; UPDRS: Unified Parkinson’s Disease Rating Scale; NMSS: Non-motor Symptom Scale; NS: not significant.