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. 2018 Nov 15;9(12):1142. doi: 10.1038/s41419-018-1181-x

Fig. 5. cfCh isolated from irradiated conditioned medium of MDA-MB-231 are devoid of exosomes but can activate H2AX in NIH3T3 cells.

Fig. 5

A Confocal images (zoomed ×60 magnification) of dually labeled cfCh isolates from irradiated conditioned medium of MDA-MB-231 cells (Upper panel). Confocal images of un-labeled cfCh isolates stained with exosome marker Hsp-70 showing absence of exosomes (lower left hand image). MDA-MB-231 cells stained with Hsp-70 are used as a positive control (lower right hand image). B Activation of H2AX in NIH3T3 cells by cfCh isolates from MDA-MB-231 cells that are devoid of exosomes (p = 0.0001).