Table 4.
90-day adverse event rates in the general population vs a matched sample of the study cohort
| General population risk % (95% CI) | Study cohort risk % (95% CI) | Risk ratio (95% CI) | ||
|---|---|---|---|---|
| Mortality30* | ||||
| Overall | 0·158% (0·157–0·159) | 0·031% (0·027–0·035) | 0·20 (0·17–0·22) | |
| <20 years | 0·007% (0·007–0·008) | .. | .. | |
| 20–39 years | 0·011% (0·011–0·012) | 0·009% (0·005–0·015) | 0·81 (0·49–1·32) | |
| 40–59 years | 0·043% (0·042–0·044) | 0·021% (0·017–0·027) | 0·50 (0·40–0·63) | |
| 60–79 years | 0·233% (0·230–0·236) | 0·061% (0·050–0·074) | 0·26 (0·22–0·32) | |
| ≥80 years | 2·043% (2·026–2·060) | 0·360% (0·238–0·524) | 0·18 (0·12–0·26) | |
| Myocardial infarction31 | ||||
| Men (<80 years) | 0·058% (0·049–0·067) | 0·046% (0·040–0·052) | 0·79 (0·64–0·97) | |
| Women (<80 years) | 0·028% (0·022–0·035) | 0·024% (0·019–0·031) | 0·88 (0·63–1·23) | |
| Pulmonary embolism32 | 0·006% (0·005–0·007) | 0·078% (0·072–0·085) | 12·99 (10·35–16·31) | |
| Stroke (<75 years)33 | 0·034% (0·030–0·039) | 0·025% (0·021–0·029) | 0·72 (0·59–0·88) | |
| Septic arthritis (native knee joint infection)34 | 0·001% (0·001–0·002)† | 0·135% (0·126–0·144) | 110·21 (81·19–149·60) | |
*
Mortality data are Office for National Statistics population-level data for England, 2016, excluding death from cancer.
†
Excludes iatrogenic causes.