Table 2B.

Main results of the included studies regarding the associations between sociodemographic factors and survival.

References	Siblings and birth order		Place of residence		Parental cohabitation/ marital status		Other individual based indicators
		HR*(95% CI)		HR*(95% CI)		HR*(95% CI)		HR*(95% CI)
ALL DIAGNOSES COMBINED
(9)	Number of full siblings<19 years				Cohabitation status
	0	1 (ref)			Alone	1 (ref)
	1	1.12 (0.95–1.31)			Together	0.82 (0.69–0.99)
	= >2	1.26 (1.03–1.53)
(5)							Rooms per person
							<1	1 (ref)
							1–1.25	0.76 (0.59–0.98)
							>1.25	0.80 (0.62–1.04)
							Living space, tertiles
							Lower	1 (ref)
							Medium	0.78 (0.60–1.02)
							Upper	0.78 (0.60–1.03)
HEMATOLOGICAL CANCERS
(9)	Number of full siblings<19 years				Cohabitation status
	0	1 (ref)			Alone	1 (ref)
	1	1.08 (0.81–1.44)			Together	0.92 (0.66–1.29)
	= >2	1.18 (0.83–1.69)
LEUKEMIA
(5)							Rooms per person
							<1	1 (ref)
							1–1.25	0.89 (0.55–1.43)
							>1.25	1.19 (0.76–1.87)
							Living space, tertiles
							Lower	1 (ref)
							Medium	0.97 (0.59–1.58)
							Upper	1.01 (0.62–1.63)
ALL
(12)			Residential area
			Urban	1 (ref)
			Mixed	1.16 (0.71-1.91)
			Rural	0.88 (0.50–1.55)
(13)	Number of children		Place of living		Marital status
	Per increase of one child	0.99 (0.80–1.25)	Rural	1.08 (0.69–1.70)	Married	0.47 (0.27–0.83)
			Semiurban	1.16 (0.74–1.81)	Other	1 (ref)
			Urban	1 (ref)
			Travel distance (km) to hospital
			<50	1 (ref)
			50–249	1.29 (0.80–2.10)
			250+	1.24 (0.82–1.87)
(14)	Birth order		Place of residence
	1st	1 (ref)	Urban	1 (ref)
	2nd	0.64 (0.37–1.10)	Mixed	1.12 (0.69–1.84)
	3rd and later	1.04 (0.55–1.95)	Rural	0.85 (0.49–1.49)
	Number of siblings
	0	1 (ref)
	1	0.86 (0.48–1.52)
	2	0.83 (0.42–1.67)
	= >3	1.58 (0.73–3.44)
(15)			Distance from tertiary center
			Univariate
			Short	1 (ref)
			Long	1.05 (0.79–1.38)
			Rurality
			Rurality
			Univariate
			Urban	1 (ref)
			Rural	1.15 (0.80–1.64)
(20)	Birth order		Place of residence
	1st	1 (ref)	Greater Copenhagen area	1 (ref)
	2nd	1.05 (0.78–1.42)	Provincial cities	1.18 (0.88–1.59)
	3rd	1.27 (0.85–1.89)	Rural areas	1.24 (0.81–1.91)
	4th and later	1.62 (0.85–3.09)	Peripheral rural areas	1.15 (0.55–2.40)
	Full siblings
	0	1 (ref)
	1	1.05 (0.76–1.46)
	2	1.19 (0.80–1.77)
	= >3	1.31 (0.83–2.08)
	Full and half siblings
	0	1 (ref)
	1	1.05 (0.71–1.55)
	2	1.28 (0.82–1.98)
	= >3	1.25 (0.76–2.05)
AML
(13)	Number of children		Place of living		Marital status
	Per increase of one child	1.07 (0.69–1.66)	Rural	1.08 (0.48–2.46)	Married	0.83 (0.23–2.94)
			Semiurban	0.52 (0.22–1.24)	Other	1 (ref)
			Urban	1 (ref)
			Travel distance (km) to hospital
			<50	1 (ref)
			50–249	0.84 (0.34–2.07)
			250+	1.06 (0.48–2.31)
(20)	Birth order		Place of residence
	1st	1 (ref)	Greater Copenhagen area	1 (ref)
	2nd	1.62 (1.01–2.59)	Provincial cities:	0.87 (0.54–1.40)
	3rd	2.22 (1.13–4.34)	Rural areas	0.83 (0.45–1.55)
	4th and later	5.76 (2.01–16.51)	Peripheral rural areas	0.54 (0.18–1.63)
	Full siblings
	0	1 (ref)
	1	1.11 (0.65–1.90)
	2	1.09 (0.59–2.00)
	= >3	2.27 (0.92–5.58)
	Full and half siblings
	0	1 (ref)
	1	1.48 (0.79–2.75)
	2	1.34 (0.67–2.67)
	= >3	2.69 (1.11–6.52)
LYMPHOMA
(5)							Rooms per person
							<1	1 (ref)
							1–1.25	0.88 (0.35–2.23)
							>1.25	0.35 (0.12–1.06)
							Living space, tertiles
							Lower	1 (ref)
							Medium	0.61 (0.22–1.70)
							Upper	0.31 (0.08–1.11)
(20)	Birth order		Place of residence
	1st	1 (ref)	Greater Copenhagen area	1 (ref)
	2nd	0.97 (0.49–1.94)	Provincial cities	0.82 (0.41–1.63)
	3rd	1.18 (0.41–3.40)	Rural areas	1.03 (0.38–2.78)
	4th and later	1.00 (0.20–5.11)	Peripheral rural areas	1.09 (0.23–5.17)
	Full siblings
	0	1 (ref)
	1	1.06 (0.44–2.59)
	2	2.26 (0.88–5.79)
	= >3	0.91 (0.26–3.20)
	Full and half siblings
	0	1 (ref)
	1	2.51 (0.63–9.92)
	2	5.25 (1.40–19.70)
	= >3	3.87 (0.92–16.31)
CNS TUMORS/TUMORS OF THE NERVOUS SYSTEM
(9)	Number of full siblings<19 years				Cohabitation status
	0	1 (ref)			Alone	1
	1	0.89 (0.67–1.18)			Together	0.70 (0.51–0.97)
	= >2	1.03 (0.72–1.48)
(5)							Rooms per person
							<1	1 (ref)
							1–1.25	0.61 (0.39–0.97)
							>1.25	0.56 (0.34–0.92)
							Living space, tertiles
							Lower	1 (ref)
							Medium	0.71 (0.43–1.17)
							Upper	0.61 (0.37–1.01)
(22)	Birth order		Place of residence at diagnosis		Cohabitation status
	1st	1.0 (ref)	Greater Copenhagen area	1.0 (ref)	Living together	1 (ref)
	2nd	0.97 (0.78–1.21)	Provincial cities	1.23 (0.98–1.56)	Living not together	1.07 (0.85–1.36)
	3rd and later	1.00 (0.75–1.32)	Rural areas	1.38 (1.00–1.90)
	Full siblings		Peripheral rural areas	1.17 (0.63–2.18)
	0	1.0 (Ref)
	1	1.12 (0.88–1.42)
	2	0.98 (0.73–1.31)
	= >3	0.87 (0.57–1.32)
	Children living in the household
	1	1.0 (Ref)
	2	1.18 (0.91–1.52)
	= >3	1.07 (0.79–1.44)
(23)			Driving distance to cancer center (miles)
			0–25	1 (ref)
			26–50	0.97 (0.78–1.20)
			>50	0.91 (0.76–1.11)
OTHER TUMORS
(9)	Number of full siblings<19 years				Cohabitation status
	0	1 (ref)			Alone	1 (ref)
	1	1.45 (1.11–1.89)			Together	0.80 (0.59–1.08)
	= >2	1.29 (0.93–1.79)
(24)			Driving distance to cancer center (miles)
			<25	1 (ref)
			25–50	1.1 (1.0–1.3)
			>50	1.1 (1.0–1.3)
(25)			Driving distance to cancer center (miles)
			Univariate
			<25	1 (ref)
			25–49	0.6 (0.2–1.9)
			> = 50	0.7 (0.2–2.0)

^*Adjusted results if not otherwise stated. RR instead of HR is presented in some studies.

ALL, Acute lymphoblastic leukemia; AML, Acute myeloid leukemia; CI, Confidence interval; CNS, Central nervous system; HR, Hazard ratio.