Table 1.

Chandler classification for laryngeal radionecrosis [8]

Symptoms	Signs	Treatment
Grade I Slight hoarseness, slight dryness	Slight oedema, telangiectasia	Symptomatic care: humidification, anti-reflux therapy, smoking cessation
Grade II Moderate hoarseness, moderate dryness	Slight oedema, telangiectasia	Symptomatic care: humidification, anti-reflux therapy, smoking cessation
Grade III Severe hoarseness with dyspnoea, moderate odynophagia and dysphagia	Severe impairment of vocal cord mobility or fixation of one cord, marked oedema, skin changes	Symptomatic care + steroids, antibiotics, tracheotomy or laryngectomy, if necessary
Grade IV Respiratory, distress, severe odynophagia, weight loss dehydration	Fistula, fetor oris, fixation of skin to larynx, airway obstruction, fever	Tracheotomy and/or laryngectomy