Table 7.

Thermal stability of 16/138 stored at elevated temperatures relative to storage at −20 °C.

Exposure		Method	Anti-Vi IgG potency relative to −20 °Ca
Duration	Temperature		Vial 1	Vial 2	GM
8.8 months	+4 °C	NIBSC ELISA	0.90	0.86	0.88
	+20 °C		0.83	0.81	0.82
	+37 °C		0.74	0.70	0.72
	+45 °C		0.39	0.38	0.38
	+4 °C	VaccZyme ELISA	0.97	1.03	1.00
	+20 °C		0.95	1.05	1.00
	+37 °C		0.82	0.96	0.89
	+45 °C		NLb	0.73	0.73

^aData produced by Laboratory 5.

^bNon linear.