Table 3.
Multivariable Cox proportional hazard model of overall survival
| Variablesa | HR (95% CI) | p-value |
|---|---|---|
| Best response of metastatic site | 0.050 | |
| CR/PR | 1 | |
| SD/PD | 1.822 (0.999–3.323) | |
| Change of CEA level | 0.024 | |
| Stable | 1 | |
| Improved | 0.564 (0.259–1.226) | 0.148 |
| Worse | 5.013 (1.477–17.017) | 0.010 |
| NA | 0.973 (0.504–1.877) | 0.935 |
| Complete Macroscopic Resection | 0.005 | |
| Yes | 1 | |
| No | 1.998 (1.233–3.238) |
CR complete response, PR partial response, SD stable disease, PD progressive disease, CEA carcinoembryonic antigen
athe final model was selected by a forward likelihood ratio method from the variables with p-value < 0.10 in a univariate Cox proportional hazard model
The bold represents statistical significance