Table 1.

Up-regulation of hypoxia pathway genes after 3 and 6 h of LPS-induced inflammation

Gene Name Unigene, GenBank	Fold Change
	3 h (n = 7)	6 h (n = 6)
Angiopoietin-like 4 (Angptl4)Rn.119611, NM_199115	20.38 (p = 0.007)	14.12 (p = 0.005)
Basic helix-loop-helix family, member (Bhlhe40) Rn.81055, NM_053328	No change	3.31 (p = 0.000)
Early growth response 1 (Egr1) Rn.9096, NM_012551	29.16 (p = 0.006)	6.67 (p = 0.046)
Immediate early response 3 (Ier3) Rn.23638, NM_212505	9.85 (p = 0.001)	No change
Plasminogen activator inhibitor type 1 (Pai1) Rn.29367, NM_012620	15.05 (p = 0.023)	No change
Solute carrier family 2 (facilitated glucose transporter), member 1 (Slc2a1, Glut1) Rn.3205, NM_138827	3.41 (p = 0.002)	No change

Only genes that showed at least a three-fold increase in expression with p < 0.05 were considered statistically significant