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(A, B) Colony survival of MCF7 cells transfected with nontargeting control siRNA and SYCE2-targeting siRNA after 4-Gy x-ray irradiation (A) and treatment with 50 μM cisplatin (B). (C, D) Sensitivities of the mock cells and FLAG-SYCE2–expressing RPE cells after treatment with ionizing radiation (C) and cisplatin (D).
