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. 2018 Sep 7;1(5):e201800157. doi: 10.26508/lsa.201800157

Figure 1. MBNL1 exon 7 is highly included in the mRNA cancer samples and cell lines.

Figure 1.

(Α) ΔPSI (ΔΨ) of splicing factors' splicing events in the TCGA prostate cancer dataset (PRAD) and (B) their relative gene expression change between normal and tumor samples. (C) PSI of MBNL1 ex7 in matched tissues from the TCGA PRCA dataset. (D) Overall expression abundance of MBNL1 in matched tissues from the TCGA PRCA dataset. Statistics performed with two-tailed, parametric, paired t test. (E) MBNL1 ex7 PSI values in normal prostate (PrEC) and prostate cancer cell lines obtained through RNA-seq (red) or using FLA-PCR data (black). Data of the FLA-PCR are representative of two independent experiments. (F) dPSI of splicing factors' splicing events in various TCGA datasets. MBNL1 ex7 event enlarged in the central graph for the different datasets. BRCA, breast carcinoma; COAD, colon adenocarcinoma; LUAD, lung adenocarcinoma; LUSC, lung squamous cell carcinoma; PRAD, prostate adenocarcinoma.