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. 2018 Sep 7;1(5):e201800157. doi: 10.26508/lsa.201800157

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© 2018 Guccione et al.

This article is available under a Creative Commons License (Attribution 4.0 International, as described at https://creativecommons.org/licenses/by/4.0/).

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Figure 5. — (A) Gene Ontology (GO) of the genes up-/down-regulated (red/blue, respectively) upon AON MBNL1 transfection in PC3 cells. (B) RNA-seq validation by qPCR for the selected subset of up-/down-regulated transcripts. In the left panel are grouped the genes involved in cell migration, whereas in the right panel are shown the genes involved in DNA replication and repair, and chromosome segregation. Data show the results of three independent biological replicates. (C) Gene Ontology of the genes alternatively spliced (yellow) upon AON MBNL1 transfection in PC3 cells. (D) RNA-seq validation by qPCR for the selected subset of differentially spliced transcripts. In the left panel are grouped the genes involved in cell migration, whereas in the right panel are shown the genes involved in DNA replication and repair, and chromosome segregation. Data show the results of three independent biological replicates.