FIG. 3.
The μRB scaffolds led to significantly enhanced MSC proliferation and cartilage matrix production compared with HGs in 3D. (A) DNA content per wet weight increased ∼3-fold in μRB scaffolds, and no significant change in DNA was observed in HGs. (B) Quantitative GAG assay showed both μRB and HG scaffolds led to significantly enhanced GAG deposition by MSCs over 21 days, with μRB scaffolds leading to ∼50% more total sGAG deposition than HG scaffolds. ns = nonsignificant (p > 0.05), **p < 0.01, ****p < 0.0001.
