FIG. 7.

Faster ability of hindlimb stepping through inclusion of E14 spinal progenitor cells. Average BMS scores are observed to increase over time for each condition; however, no significant difference between groups over time was observed as determined by one-way analysis of variance with repeated measures using a Tukey post-hoc test (A). By 8 weeks, significantly more mice that received bridges with E14 transplants were able to perform stepping (BMS = 4) on ipsilateral hindlimb affected by the lateral hemisection as determined by chi-squared test [(B); *p < 0.01, n = 11 mice per bridge condition]. By 6 months, 90% of mice receiving either E14 or adult transplants achieved stepping compared to 70% transplanted with blank bridges. ANOVA, analysis of variance; BMS, Basso Mouse scale.